The discipline of pharmacology encompasses both how drugs affect the body (pharmacodynamics), as well as how the body affects drugs (pharmacokinetics). Because it is such an interdisciplinary field, pharmacology necessarily is built upon a foundation consisting of nearly every other basic science discipline that is part of a medical school curriculum. You must have a good grasp of physiology, pathology, biochemistry, microbiology, and molecular biology in order to study pharmacology. Even many disciplines that people have not traditionally associated with pharmacology are turning out to be essential for understanding pharmacology, such as anatomy and genetics. In fact, one of the hottest areas in pharmacology right now is pharmacogcnomics, where a patient's treatment is tailored based upon his or her unique genetic makeup. This edition of High-Yield Pharmacology has been substantially updated and revised. Specifically, new sections on biologies have been added in the appropriate chapters, as well as several new figures and tables. In addition, the cardiovascular pharmacology chapter has been expanded and split in half, reflecting the rapid growth in the pharmacology of this area. Readers who desire a very brief review can read the bolded printed text, which highlights the most important concepts in each chapter. In addition, the index can be used to help you review the class of every drug in the book. It is unfortunate that many medical students approach pharmacology as just a list of drug names and side effects that must be memorized for the United States Medical Licensing Examination. You may be using this book to review pharmacology for Step 1 of the USMLE, and I hope you will find it helpful as you prepare. But I also hope that it will give you at least an inkling of how interesting and dynamic the field of pharmacology is. Please feel free to contact me at if you have any comments or suggestions about the book.
PrefaceAcknowledgmentsI Pharmacokinetics: General PrinciplesII Pharmacokinetics: Administration and Absorption of DrugsIII Pharmacokinetics: Distribution of DrugsIV Pharmacokinetics: Metabolism of DrugsV Pharmacokinetics: Elimination of Drugs and Drug MetabolitesVI PharmacodynamicsVII Age-Dependent PharmacologyVIII Regulations Governing the Development of New DrugsI Overview of the Autonomic Nervous SystemII Parasympathomimetics111 Cholinesterase InhibitorsIV Parasympathetic Blocking Drugs (Antimuscarinics)V Ganglionic Blocking DrugsVI Neuromuscular Blocking DrugsVII SympathomimeticsVIII a-Adrenoceptor AntagonistsIX (i-Adrenoceptor AntagonistsX Adrenergic Neuron-Blocking DrugsXI Drugs for GlaucomaI Principles of General AnesthesiaII Inhalation AnestheticsIII Intravenous AnestheticsIV Local AnestheticsV Sedative-Hypnotic and Antianxiety DrugsVI AnticonvulsantsVII Antipsychotic Drugs (Neuroleptics)VIII Lithium Carbonate……